Netflix (NASDAQ: NFLX ) has traditionally been a notable target among short-sellers. Even if the bears have been running for cover lately, the stock still carries a relatively high short interest ratio of around 10%. But shorting Netflix has been a losing proposition over the last years, and the way things are going, it could also be a very expensive mistake on a forward-looking basis.
Competitive strengths
One of the most popular arguments among Netflix short-sellers is that the company lacks the competitive strengths to succeed in the long term. Amazon.com (NASDAQ: AMZN ) is usually seen as the most challenging competitor for Netflix over the coming years.
Amazon Prime offers free two-day shipping, access to the Kindle Owners' Lending Library, and more than 40,000 tittles available for streaming via its Prime Instant online video service for a conveniently low price of $79 per year. The service now has "tens of millions" of members, according to the company, and it gained more than 1 million new members in the third week of December alone, so it continues growing at full speed.
Top Shipping Stocks To Own For 2014: CirTran Corp (CIRC)
CirTran Corporation, incorporated on March 23, 1987, manufactures, markets, and distributes internationally an energy drink under a license with Playboy Enterprises, Inc. (Playboy) through its subsidiary, CirTran Beverage Corporation. It operates in Beverage Distribution and Contract Manufacturing segments. In the United States, it provides a mix of high- and medium-volume turnkey manufacturing services and products using various high-tech applications for electronics original equipment manufacturers (OEMs) in the communications, networking, peripherals, gaming, law enforcement, consumer products, telecommunications, automotive, medical, and semiconductor industries. The Company�� services include pre-manufacturing, manufacturing, and post-manufacturing services.
Beverage Distribution
CirTran Beverage Corporation (CirTran Beverage) manufactures, markets, and distributes Playboy-licensed energy drinks, flavored water beverages, and related merchandise through various distribution channels. As of December 31, 2012, the Company had 65 countries throughout Europe, Africa, Australia, the Pacific, and the Middle East.
Contract Marketing
CirTran Products Corp. pursues contract-manufacturing relationships in the domestic consumer products markets, including products in areas, such as home/garden, kitchen, health/beauty, toys, licensed merchandise, and apparel for film, television, sports, and other entertainment properties. The Company concentrates its product development efforts into three areas: home and kitchen appliances, beauty products, and licensed merchandise. Through CirTran - Asia, Inc., the Company designs, manufactures, and supplies products in the international electronics, consumer products, and general merchandise industries for various marketers, distributors, and retailers selling overseas. This subsidiary provides manufacturing services to the direct-response and retail consumer markets.
The Company competes with Hansen�! � Energy, Diet Red, Monster Energy, Lost Energy, Joker Mad Energy, Ace Energy, Unbound Energy, Rumba energy juice, Red Bull, Rockstar, Full Throttle, No Fear, Amp, Adrenaline Rush, 180, Extreme Energy Shot, Red Devil, Rip It, NOS, Boo Koo, and Vitaminenergy.
Advisors' Opinion:- [By CRWE]
Last Friday, CIRC remained (0.00%) +0.000 at $.0005 at the close (ref. google finance August 30, 2013 ��Close).
CirTran Corporation has recently filed its Quarterly Report on Form 10-Q for the period ended June 30, 2013, showing continued growth in sales and a dramatic improvement in profits. CirTran�� sales were again driven by its Playboy Energy Drink line, which has grown to represent nearly 98% of revenues.
For the quarter, CirTran previously reported sales of $1,096,691, a 247% increase over the $315,755 reported for the same period a year ago. For the six months ended June 30, 2013, CirTran reported sales of 1,964,843, a 110% improvement over the $934,455 reported for the first half of 2012.
Top Shipping Stocks To Own For 2014: Monster Beverage Corp (MNST)
Monster Beverage Corporation, formerly Hansen Natural Corporation, incorporated on April 25, 1990,is a holding company. The Company develops, markets, sells and distributes alternative beverage. The alternative beverage category combines non-carbonated ready-to-drink iced teas, lemonades, juice cocktails, single-serve juices and fruit beverages, ready-to-drink dairy and coffee drinks, energy drinks, sports drinks, and single-serve still water (flavored, unflavored and enhanced) with new age beverages, including sodas that are considered natural, sparkling juices and flavored sparkling beverages. It has two reportable segments, namely Direct Store Delivery (DSD), whose principal products comprise energy drinks, and Warehouse (Warehouse), whose principal products comprise juice-based and soda beverages. The DSD segment develops, markets and sells products primarily through an exclusive distributor network, whereas the Warehouse segment develops, markets and sells products primarily directly to retailers. Corporate and unallocated amounts that do not relate to the DSD or Warehouse segments specifically, have been allocated to Corporate and Unallocated.
During the year ended December 31, 2012, it continued to expand its existing product lines and flavors and further develop its distribution markets. In particular, it continued to focus on developing and marketing beverages that fall within the category generally described as the alternative beverage category. During the year ended December 31, 2012, it introduced a number of new products, including Monster Rehab Tea + Orangeade + Energy, a non-carbonated energy drink with electrolytes, Monster Energy Zero Ultra, a carbonated energy drink which contains zero calories and zero sugar, bermonster Energy Brew, a non-alcoholic energy drink, manufactured using a brewed fermentation process, Hansen�� Coconut Water, in original and tropical flavors, packaged in re-sealable Tetra Prisma boxes, Peace Tea Cranberry, Pink Lemonade and Texas-Style Sweet ! Tea, ready-to-drink iced teas, Monster Cuba-Lima, a carbonated lime flavored non-alcoholic energy drink, Monster Energy Dub Edition Baller�� Blend, a carbonated punch + energy drink and Monster Energy Dub Edition Mad Dog, a carbonated punch + energy drink.
DSD Segment
Monster Energy Drinks offers products under the Monster Energy drink product line: Monster Energy, Lo-Carb Monster Energy, Monster Energy Assault, Monster Khaos, Monster M-80 (named Ripper in certain countries), Monster MIXXD, Monster Energy Absolutely Zero, Monster Energy Import and Import Light, Monster Energy Dub Edition Baller�� Blend, Monster Energy Dub Edition Mad Dog, M3 Monster Energy Super Concentrate energy drinks, bermonster Energy Brew, Monster Energy Zero Ultra and Monster Cuba-Lima.
Java Monster Coffee + Energy Drinks - A line of non-carbonated dairy based coffee + energy drinks. It offers products under the Java Monster product line: Java Monster Kona Blend, Java Monster Loca Moca, Java Monster Mean Bean, Java Monster Vanilla Light, Java Monster Irish Blend and Java Monster Toffee. Monster Energy Extra Strength Nitrous Technology Energy Drinks - A line of carbonated energy drinks containing nitrous oxide. It offer products under the Monster Energy Extra Strength Nitrous Technology product line: Super Dry, Anti Gravity and Black Ice.
-Presso Monster Coffee + Energy Drinks - A line of non-carbonated dairy based coffee + energy drinks. It offers products under the X-Presso Monster coffee + energy drinks product line: X-Presso Monster Hammer and X-Presso Monster Midnite.
Monster Rehab Tea + Energy Drinks - A line of non-carbonated energy drinks with electrolytes. It offers products under the Monster Rehab drink line: Monster Rehab Tea + Lemonade + Energy, Monster Rehab Rojo Tea + Energy, Monster Rehab Green Tea + Energy, Monster Rehab Protean + Energy and Monster Rehab Tea + Orangeade + Energy.
Worx Energy Energy Shots - A line of energy suppleme! nts which! contains zero calories and zero sugar. It offers products under the Worx Energy energy shot product line: Original Formula and Extra Strength.
Peace Tea Iced Teas - A line of ready-to-drink iced teas. It offers products under the Peace Tea product line: green tea, imported Ceylon tea, sweet lemon tea, razzleberry tea, cranberry tea, pink lemonade tea, Texas-style sweet tea and Caddy Shack tea + lemonade.
Warehouse Segment
Hansen�� brand sodas have been a natural soda brand on the West Coast of the United States for more than 30 years and are made with natural flavors. Hansen�� brand sodas, sweetened with cane sugar, and Hansen�� Diet Sodas, sweetened with Splenda no calorie sweetener and Acesulfame-K, contain no preservatives, sodium, caffeine or artificial colorings. It offers sodas under the Hansen�� brand name: Hansen�� Sodas, Hansen�� Diet Sodas and Hansen�� Natural Mixers, as well as Hansen�� Sparkling Waters, in a variety of flavors.
Its Blue Sky products contain no preservatives, artificial sweeteners, caffeine (other than its Blue Sky energy drinks) or artificial coloring and are made with sugar and natural flavors. It offers products under the Blue Sky product line: Blue Sky Natural Soda, Blue Sky Zero Calorie Sodas (sweetened with Truvia brand stevia extract, an all natural sweetener), Blue Sky Premium Sodas, Blue Sky Organic Natural Sodas, Blue Sky Seltzer Waters, Blue Sky Blue Energy drinks, Blue Sky Zero Calorie Blue Energy drinks, Blue Sky Caf Energy drinks and Blue Sky Recover Energy drinks.
Its original Hansen�� energy drinks compete in the functional beverage category, namely, beverages that provide a benefit in addition to simply delivering refreshment. It offers products under the Hansen�� energy drink product line: Hansen�� Natural Energy Pro, Hansen�� Energy Diet Red and Hansen�� Natural Stamina Pro.
Its fruit juice product line includes Hansen�� Natural Apple Juice, Ha! nsen�� ! Natural Grape Juice, White Grape Juice, Pineapple Juice, Apple Grape Juice, Apple Strawberry Juice, Orange Juice, Cranberry Juice, Cranberry-Apple Juice, Cranberry-Grape Juice, Ruby Red Grapefruit Juice, and Organic Apple Juice. In March 2012, it added Hansen�� Natural Apple Orange Pineapple Juice which contains 100% juice as well as 120% of the United States Recommended Daily Allowances (the USRDA) for vitamin C. It also offer Hansen�� Natural Lo-Cal juice cocktails, a line of all natural, low-calorie cocktails in four flavors. The Lo-Cal juice cocktails are sweetened with Truvia sweetener. Hansen�� juice products compete in the shelf-stable juice category.
It offers a number of aseptically packed boxed juice products, including its dual-branded multi-vitamin 100% juice line, which itsell in conjunction with Costco Wholesale Corporation (Costco) through Costco stores. It offers its Hansen�� Natural line of multi-vitamin 100% juices to other customers. These multi-vitamin juices contain eleven essential vitamins and six essential minerals and are available in a variety of flavors. In February 2012, it added Hansen�� Natural Organic Apple Juice, a 100% USDA Certified Organic Apple Juice with 100% of the USRDA for vitamin C.
Its Hansen�� Junior Juice product line is a 100% juice line targeted at toddlers and preschoolers. These juices have added calcium and all flavors contain 100% of the daily recommended allowance of vitamin C. It also offers organic juices as well as Hansen�� Organic Junior Water, a lightly flavored reduced calorie beverage, both of which contain 100% of the daily recommended allowance of vitamin C. In addition, it offers Junior Juice Coconut Water Twist, a line of fruit and coconut water juices containing 100% of the daily recommended allowance of vitamin C.
Its Hubert�� Lemonade is a line of premium ready-to-drink lemonades. Hubert�� Lemonade is sweetened with cane sugar and Truvia sweetener. Hubert�� Lemonade i! s all nat! ural and contains no preservatives, artificial sweeteners, caffeine, or artificial colorings. It offers products under the Hubert�� Lemonade product line: Strawberry Lemonade, Limeade, Mango Lemonade, Honey Lemonade, Raspberry Lemonade and Original Lemonade. It added Cherry Limeade and Blackberry Lemonade flavors to the product line in February 2012 and October 2012, respectively. In July 2012, it introduced 4-count multi-packs of select flavors.
Hubert�� Half & Half is sweetened with cane sugar and Truvia sweetener, and contains no preservatives, artificial sweeteners, or artificial colorings. Its Fruit and Tea Stix product line is an all-natural, low-calorie powder drink mix line, sweetened naturally with Truvia sweetener. Its Angeleno Aguas Frescas is a line of premium ready-to-drink aguas frescas. Angeleno Aguas Frescas are sweetened with cane sugar and real fruit juice and contain no preservatives, artificial sweeteners, caffeine, or artificial colorings. It offers flavors under the Angeleno Aguas Frescas product line: Mango, Melon, Pineapple, Jamaica (Hibiscus) and Tamarindo. Its Hansen�� Natural PRE products include a line of prebiotic and probiotic digestive wellness ready-to-drink beverages and powder drink mixes, containing specially formulated blends by Jarrow Formulas. PRE prebiotic ready-to-drink beverages are sweetened with either cane sugar or stevia. PRE probiotic powder drink mixes are sweetened with cane sugar and stevia. In March 2012, it introduced Hansen�� Natural Coconut Water, a line of premium 100% Coconut Waters available in Pure and Tropical flavors.
The Company competes with TCCC, PepsiCo, Inc. (PepsiCo), The Dr. Pepper Snapple Group, Inc. (the DPS Group), Red Bull Gmbh, Kraft Foods, Inc., GlaxoSmithKline plc, Nestle Beverage Company, Tree Top Inc. (Tree Top), Ocean Spray Cranberries Inc. (Ocean Spray), Red Bull, Rockstar, Full Throttle, No Fear, Amp, Adrenaline Rush, NOS, Venom, Redline, 180, Red Devil, Rip It, Xenergy, 5-Hour Energy ! Shots, Mi! O Energy, Stacker 2, VPX Redline Energy Shots, Red Bull, Rockstar, Burn, V-Energy, Lucozade, Adrenaline Rush, Power Play, Mother, Hell, Shock, Tiger, Boost, Gladiator, TNT, Shark, Hot 6, Nalu, Battery, Bullit, Flash Up, Black, Non-Stop, Bomba, Semtex, Starbucks Frappuccino, Starbucks Double Shot, Starbucks Double Shot Energy Plus Coffee , other Starbucks coffee drinks, Rockstar Roasted, Seattle�� Best, illy issimo coffee, Full Throttle Coffee, Arizona, Lipton, Snapple, Nestea, Xing Tea, Honest Tea, Gold Peak Tea, Fuze Tea, the DPS Group, Cott Corporation and National Beverage Corporation, Jones Soda Co., Crystal Geyser, J.M. Smucker Company, Reeds, Inc., Zevia, Tree Top, Mott��, Martinelli��, Welch��, Ocean Spray, Tropicana, Minute Maid, Langers, Apple , Eve, Seneca, Northland, Juicy Juice, Old Orchard, Calypso, Simply Lemonade, Minute Maid, Cabana, Tropicana, Newman�� Own, Vita Coco, ZICO and O.N.E.
Advisors' Opinion:- [By Rich Bieglmeier]
Monster Beverage Corporation (MNST) results for its third quarter ended September 30, 2013 will be released on Thursday, November 7, 2013 after the close of the market. The company also said that chairman and chief executive officer Rodney Sacks and vice chairman and president Hilton Schlosberg will host an investor conference call that same day at 2:00 p.m. Pacific Time to review the company's financial results and operations.
- [By John Divine]
"Alternative beverage" and energy drinks company Monster Beverage (NASDAQ: MNST ) logged some of the steepest losses in the index today, losing 3.6%. There wasn't much material news today for investors to be fearful of, but the same can't be said for the last several months. One perpetual setback for the company is the legal risk it assumes for selling and marketing its controversial energy drinks. In May, for example, the city of San Francisco sued Monster for marketing its caffeine-heavy drinks to kids without concern for potential health risks.�
Best Income Stocks To Invest In 2014: Volcano Corporation(VOLC)
Volcano Corporation designs, develops, manufactures, and commercializes intravascular ultrasound (IVUS) and fractional flow reserve (FFR) products used in the diagnosis and treatment of vascular and structural heart disease. It offers multi-modality consoles, which are marketed as stand-alone units that can be integrated into hospital-based interventional surgical suites, such as catheterization laboratories. The company provides IVUS products, including single-procedure disposable phased array and rotational IVUS imaging catheters; and additional functionality options comprising virtual histology tissue characterization, and ChromaFlo stent apposition analysis. It also offers FFR products, such as pressure and flow consoles, and single-procedure disposable pressure and flow guide wires used to measure the pressure and flow characteristics of blood around plaque enabling physicians to gauge the plaque?s physiological impact on blood flow and pressure. In addition, the com pany develops and manufactures optical monitors for the telecommunication industry; laser and non-laser light sources; optical engines used in the medical OCT imaging systems and advanced photonic components; and sub-systems used in spectroscopy and other industrial applications. Its products under development include image-guided therapy device and micro and thrombectomy catheters. The company?s ongoing clinical studies comprise assessment of dual anti-platelet therapy with drug-eluting stents; vascular evaluation for revascularization; fractional flow reserve and intravascular ultrasound relationship study; adensonine vasodilation independent stenosis evaluation; and evaluation of XIENCE PRIME. It sells its products through direct sales force and distributors, as well as through third parties supply and distribution agreements primarily in the United States, Japan, Europe, the Middle East, Africa, and internationally. The company was founded in 2000 and is headquartered i n San Diego, California.
Advisors' Opinion:- [By Monica Gerson]
Volcano (NASDAQ: VOLC) shares dropped 15.89% to $20.49 in pre-market trading after the company reported Q3 revenue. JP Morgan downgraded the stock from Overweight to Neutral and lowered the price target from $29.00 to $24.00.
- [By Teresa Rivas]
Shares of Volcano (VOLC) were up 8% in afternoon trading, following the company�� better-than-expected second-quarter earnings report and a spate of positive analyst commentary.
The medical device company said it earned 3 cents a share, whereas analysts were expecting a one cent per share loss. Revenues of $101.3 million also topped consensus estimates of $97.9 million.
Volcano also issued mixed guidance for the full year, saying it expects to earn between 3 and 5 cents a share on revenue of $394 million to $400 million. Analysts are modeling for earnings per share of a nickel on $395.8 million in sales.
Analysts were also largely positive about the quarter. Canaccord Genuity�� Jason Mills and Jeffery Chu upgraded the stock from Hold to Buy and boosted their price target by $5 to $26 on the news. ��olid or improving revenue growth trends and margin expansion are tried and true drivers of small-cap med-tech multiples. However, since October 2010, VOLC has lost over 20% of its value amid declining growth (admittedly from a high level) and inconsistent gross margin performance, which drove multiple contraction to its current discount relative to the broad comp group. However, improving trends in the core IVUS business, easing Y/Y comps, strong margin expansion potential via manufacturing transition to Costa Rica in 2014, and several catalysts on the horizon (e.g., new products, clinical data), portend a more favorable risk/reward profile in the stock at current trading levels.��/p>
Raymond James analyst Jayson Bedford reiterated an Outperform rating on the stock and boosted his target price by $1 to $25. �� re-acceleration to double-digit constant currency growth and guidance that was maintained should help improve investor sentiment. At 2.5x EV/Sales, we do not believe investors are giving Volcano credit for its 9-11% top-line growth profile, with visibility into 70% gross margins. Additionally, we expect investor enthusiasm to inc
- [By Ben Levisohn]
Strategist Andrew Garthwaite and team explain why companies like Sprint (S),� American Water Works (AWK), Volcano (VOLC), Southern (SO) and Level 3 Communications�(LVLT) could get hit by the taper:
- [By Ben Levisohn]
Instead of an eruption, Volcano (VOLC) got an earnings-induced collapse instead.
Associated PressMedical-device maker Volcano said its third quarter profit would miss Wall Street forecasts, and 2013 sales would also disappoint. And 2014? Well, that didn’t look too exciting other.
JPMOrgan analyst Christopher Pasquale and team have had enough:
We are downgrading VOLC shares to Neutral from Overweight following the company�� negative 3Q preannouncement and disappointing initial 2014 growth outlook Monday after the close. While we continue to see significant long-term potential for Volcano�� technologies, we are concerned by persistent headwinds to its core IVUS franchise and slowing FFR growth. With our conviction in a pipeline-driven reacceleration reduced and visibility into meaningful new growth drivers unlikely for several quarters, we are moving to the sidelines.
Canaccord Genuity’s Jason Mills and Jeffrey Chu also cut Volcano to Hold–just a quarter after upgrading it–and even today’s drop might not make it worth buying. They explain why:
Our upgrade of VOLC last quarter was predicated on the improving trends in the core IVUS business, FFR continuing as a long-term growth engine, and the potential material gross margin expansion. While Q3 results included pockets of good news, adverse trends predominated.
While US IVUS rebounded modestly, driven by peripheral IVUS (+40% Y/Y), IVUS and FM results in Japan were very disconcerting to us (-19%, +8%, respectively), and portend share loss, in our estimation. Also, while we still expect significant gross margin expansion long term, it seems we may have to wait longer than expected.In sum, we would not aggressively buy weakness unless the stock is over-penalized on these results – i.e. below $20.
While shares of Volcano have dropped 15% to $20.74, large-cap medical device companies are having a solid day. Boston Scienti
Top Shipping Stocks To Own For 2014: Select Sector Financial Select Sector SPDR Fund (XLF)
Financial Select Sector SPDR Fund (the Fund) seeks to provide investment results that correspond to the price and yield performance of the Financial Select Sector of the S&P 500 Index (the Index). The Index includes financial service firms with diversified business lines ranging from investment management to commercial and investment banking.
The Fund utilizes a passive or indexing investment approach to invest in a portfolio of stocks that seek to replicate the Index. The Fund�� investment advisor is SSgA Funds Management, Inc.
Advisors' Opinion:- [By Ben Levisohn]
The�Consumer Discretionary Select Sector SPDR�(XLY) has dropped 1.1% to $60.39, while the�Financial Select Sector SPDR(XLF) is off 0.9% at $20.23.� Hardest hit is the�Utilities Select Sector SPDR (XLU), which has dropped 1.6% to $37.32, while the Industrial Select Sector SPDR ETF (XLI) has fallen 1% to $46.49. The�Technology Select Sector SPDR (XLK) is the top performer: It�� down 0.5% at $32.39.
- [By Holly LaFon]
As the financial sector began to heal in 2012, it was reflected in the price of stocks ��the Financial Select Sector SPDR (XLF) increased 31% over the past year, more than doubling from its 2009 lows. It also catapulted Berkowitz�� fund to the top-performing percentile of mutual funds this year.
- [By Ben Levisohn]
Shares of Bank of America have fallen 1.8% to $14.34 today, while JPMorgan Chase (JPM), which is facing a mortgage probe of its own, has dropped 2% to $53.07. Citigroup (C) has declined 2.2% to $50.48, while Goldman Sachs (GS) is off 1.8% at 160.44. The Financial Select Sector SPDR ETF (XLF) has fallen 1.7% to $20.02 today.
Top Shipping Stocks To Own For 2014: Usinas Siderurgicas de Minas Gerais SA Usiminas (USIM3)
Usinas Siderurgicas de Minas Gerais SA Usiminas, formerly COSIPA - Companhia Siderurgica Paulista, is a Brazil-based company engaged in the steel industry. The Company is principally involved in the production and sale of flat rolled steel. The Company and its subsidiaries operate throughout the steel production process. The Company divides its business into four segments: Mining; Solutions Usiminas and Automotive Usiminas, both units are related to steel processing and unit of capital goods and services through Usiminas Mechanics. The Company provides its products to various industrial sectors, such as automotive, marine, oil and gas, construction, machinery and equipment, among others. The Company offers its services both in Brazil and abroad. On December 20, 2013, the Company concluded transfer of the total stake in the share capital of Automotiva Usiminas SA to Aethra Sistemas Automotivos SA. Advisors' Opinion:- [By Ney Hayashi]
The Ibovespa rebounded from its biggest two-day drop since July 2012 as Usinas Siderurgicas de Minas Gerais SA (USIM3) led steelmakers higher, following a rally in commodity prices.
Top Shipping Stocks To Own For 2014: Shire PLC (SHPG)
Shire plc (Shire), incorporated on January 28, 2008, is a specialty biopharmaceutical company that focuses on meeting the needs of the specialist physician. Shire focuses its business on attention deficit and hyperactivity disorder (ADHD), gastrointestinal (GI) diseases, human genetic therapies (HGT) and regenerative medicine (RM), as well as opportunities in other therapeutic areas. As of December 31, 2012, the Company�� products included VYVANSE/VENVANSE (lisdexamfetamine dimesylate), ADDERALL XR (mixed salts of a single-entity amphetamine), INTUNIV (extended release guanfacine), EQUASYM (methylphenidate hydrochloride) modified release (XL), LIALDA (mesalamine)/ MEZAVANT(mesalazine), PENTASA (mesalamine), RESOLOR (prucalopride), FOSRENOL (lanthanum carbonate), XAGRID (anagrelide hydrochloride), REPLAGAL (agalsidase alfa), ELAPRASE (idursulfase), VPRIV (velaglucerase alfa), FIRAZYR (icatibant) and DERMAGRAFT(Human Fibroblast-Derived Dermal Substitute). As of December 31, 2012, the Company�� products under development included INTUNIV (extended release guanfacine), VYVANSE/VENVANSE (lisdexamfetamine dimesylate), INTUNIV, Guanfacine Carrier Wave, LIALDA (mesalamine)/MEZAVANT (mesalazine), RESOLOR (prucalopride), RESOLOR (prucalopride), SPD 557(M0003), XAGRID, VYVANSE (lisdexamfetamine dimesylate), REPLAGAL (agalsidase alfa), HGT-4510, HGT-2310, HGT-1410, HGT-1110, HGT-3010, and DERMAGRAFT. On January 31, 2012, the United States Food and Drug Administration approved VYVANSE for the maintenance treatment of ADHD in adults. In March 2013, it announced the acquisition Of Premacure AB. In January 2014, Shire Plc sold its DERMAGRAFT assets to Organogenesis Inc. In January 2014, Shire Plc acquired 79.5% interest in ViroPharma Inc.
VANSE/ VENVANSE
VYVANSE is a New Chemical Entity (NCE) and is the pro-drug stimulant for the treatment of ADHD, where the amino acid l-lysine is linked to d-amphetamine. VYVANSE is therapeutically inactive until metabolized in the body. The United Stat! es Food and Drug Administration approved VYVANSE as a once-daily treatment for children aged 6 to 12 with ADHD in February 2007, for adults in April 2008 and for adolescents aged 13 to 17 in November 2010. VYVANSE is available in the United States in six dosage strengths: 20 milligram, 30 milligram, 40 milligram, 50 milligram, 60 milligram and 70 milligram. Health Canada approved VYVANSE for the treatment of ADHD in pediatric patients aged 6 to 12 in February 2009, and for adolescents and adults in November 2010. In April 2012, ANVISA, the Brazilian health authority, granted marketing authorization approval for lisdexamfetamine dimesylate for the treatment of ADHD in children aged 6-12.
ADDERALL XR
ADDERALL XR is an extended release treatment for ADHD, which uses MICROTROL drug delivery technology and is designed to provide once-daily dosing. It is available in 5 milligram, 10 milligram, 15 milligram, 20 milligram, 25 milligram and 30 milligram capsules and can be administered either as a capsule or sprinkled on soft food. The United States Food and Drug Administration has approved ADDERALL XR as a once-daily treatment for children aged 6 to 12 with ADHD, for adults in and for adolescents aged 13 to 17. Teva Pharmaceutical Industries, Ltd. (Teva) and Impax Laboratories, Inc. (Impax) commenced commercial shipment of their authorized generic versions of ADDERALL XR in April and October 2009, respectively. Shire receives royalties from Impax�� sales of authorized generic ADDERALL XR.
INTUNIV
INTUNIV is a selective alpha-2A receptor agonist indicated for the treatment of ADHD. Alpha-2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signalling in the prefrontal cortex (Cell. 2007; 129:397-410). INTUNIV is non-scheduled and has no known potential for abuse or dependence. The United States Food and Drug Administration approved INTUNIV in September 2009, as a once-daily monotherapy treatment of ADHD in children and adolesce! nts aged ! 6 to 17. It is available in 1 milligram, 2 milligram, 3 milligram and 4 milligram tablets.
EQUASYM
Shire has acquired from UCB the worldwide rights (excluding the United States, Canada and Barbados) to EQUASYM (methylphenidate hydrochloride) IR and XL for the treatment of ADHD in children and adolescents aged 6 to 18. At December 31, 2012,EQUASYM XL was commercially available in 10 countries in 10mg, 20mg and 30mg strengths. EQUASYM XL is marketed in Mexico and South Korea under the trade name METADATE CD.
LIALDA/MEZAVANT
LIALDA is indicated for the induction ofmild to moderately active UC and for the maintenance of remission of UC. The addition of the indication for maintenance of remission of ulcerative colitis was approved by Health Canada in February 2011, and by the United States Food and Drug Administration in July 2011. LIALDA is once-daily oral formulation of mesalamine indicated for the induction and maintenance of remission. As of December 31, 2012, LIALDA/MEZAVANT (this product is marketed outside the United States as MEZAVANT) was commercially available in 19 countries either directly or through distributor arrangements.
PENTASA
PENTASA controlled release capsules are approved in the United States (marketed by Shire in the United States and by Ferring outside of the United States) and indicated for the induction of remission and for the treatment of patients with mild to moderately active ulcerative colitis. PENTASA is an ethylcellulose-coated, controlled release capsule formulation designed to release therapeutic quantities of mesalamine throughout the gastrointestinal tract. PENTASA is available in the United States in 250 milligram and 500 milligram capsules.
RESOLOR
RESOLOR (prucalopride), a 5-HT4 receptor agonists that stimulates gastrointestinal motility and acts primarily on different parts of the lower gastrointestinal tract (enterokinetic). In October 2009, RESOLOR was appr! oved by t! he EMA throughout the European Union as a once daily oral treatment for symptomatic treatment of chronic constipation in women in whom laxatives fail to provide adequate relief. In July 2010, Swissmedic granted RESOLOR marketing authorization in Switzerland for the treatment of idiopathic chronic constipation in adults. RESOLOR is available in milligram and 2 milligram dose strengths, both for once-daily dosing. At December 31, 2012, RESOLOR was available in six European Union countries. Formulated as a chewable tablet, FOSRENOL is available in 500 milligram, 750 milligram and 1,000 milligram dosage strengths.
XAGRID
XAGRID (anagrelide hydrochloride) is marketed in Europe for the reduction of elevated platelet counts in at-risk ET patients. XAGRID has been granted orphan drug status in the European Union. In the United States, anagrelide hydrochloride is sold by the Company under the name AGRYLIN for the treatment of thrombocythemia secondary to a MPD.
REPLAGAL
REPLAGAL is for the treatment of Fabry disease. Fabry disease is a genetic disorder resulting from a deficiency in the activity of the lysosomal enzyme alpha-galactosidase A, which is involved in the breakdown of fats. REPLAGAL is a human alpha-galactosidase A protein made in human cells that replaces the deficient alpha-galactosidase A with an active enzyme to ameliorate certain clinical manifestations of Fabry disease. At December 31, 2012, REPLAGAL was approved in 46 countries.
ELAPRASE
ELAPRASE is a treatment for Hunter syndrome (also known as Mucopolysaccharidosis Type II or MPS II). Hunter syndrome is a genetic disorder mainly affecting males that interferes with the body's ability to break down and recycle waste substances called mucopolysaccharides, also known as glycosaminoglycans (GAGs). ELAPRASE was approved by the United States Food and Drug Administration and granted marketing authorization by the EMA for the long term treatment of patients with Hunter ! syndrome.! ELAPRASE has been granted orphan drug by both the United States Food and Drug Administration and the EMA. ELAPRASE received approval from the Ministry of Health, Labour and Welfare in Japan. At December 31, 2012, ELAPRASE was approved in 51 countries.
VPRIV
VPRIV is a treatment for Type 1 Gaucher disease. Gaucher disease is an inherited genetic disorder, which results in a deficiency of the lysosomal enzyme beta-glucocerebrosidase. VPRIV was approved by the United States Food and Drug Administration in February 2010, for the long-term treatment of patients with Type 1 Gaucher disease. The EMA approved the marketing authorization for the use of VPRIV in August 2010. VPRIV was authorized as an orphan medicine through the Centralised Procedure in Europe. At December 31, 2012, VPRIV was approved in 38 countries.
FIRAZYR
FIRAZYR is a peptide-based therapeutic developed for the symptomatic treatment of acute attacks of HAE. In July 2008 the EMA granted marketing authorization throughout the European Union for the use of FIRAZYR for the symptomatic treatment of acute attacks of HAE, and in May 2011 approved FIRAZYR for self-administration after training in subcutaneous injection technique by a healthcare professional. In August 2011, the United States Food and Drug Administration granted marketing approval for FIRAZYR in the United States for treatment of acute attacks of HAE in adults aged 18 and older. After injection training, patients may self-administer FIRAZYR. FIRAZYR has been granted orphan drug by both the United States Food and Drug Administration and the EMA. At December 31, 2012, FIRAZYR was approved in 38 countries globally.
DERMAGRAFT
DERMAGRAFT is a bio-engineered skin substitute that assists in restoring damaged tissue. DERMAGRAFT is indicated for use in the treatment of full-thickness Diabetic foot ulcers (DFU) greater than six weeks in duration, which extend through the dermis, but without tendon, muscle, joint capsu! le, or bo! ne exposure. DERMAGRAFT is approved by the United States Food and Drug Administration as a Class III medical device for the treatment of DFUs. DERMAGRAFT is also approved for the treatment of DFUs in South Africa, Israel and Singapore.
The Company competes with Shionogi & Co., Ltd., Janssen-Cilag, Novartis, Medice, Eli Lilly, Warner Chilcott, Synergy Pharmaceuticals, Inc., ARYx Therapeutics, Theravance, Inc., Sucampo Pharmaceuticals, Inc., Albireo, Actelion Ltd., Protalix BioTherapeutics Inc, Genzyme, CSL Behring, Pharming Group N.V., ViroPharma, Dyax Corporation, Organogenesis, Healthpoint, Soluble System, KCI, Smith & Nephew, Aurobindo and Apotex.
Advisors' Opinion:- [By Alexander Maxwell]
The market for the treatment of chronic diabetic foot ulcers has been growing and larger companies have been taking notice. Many large pharmaceutical companies have their own treatments for chronic diabetic foot ulcers. The space has also caused some major acquisitions. In 2011, Shire� (NASDAQ: SHPG ) acquired�a drug called Dermagraft for the treatment of slow-healing diabetic foot ulcers, through its $750 million acquisition of�Advanced BioHealing. Dermagraft has been a rather lucrative product for Shire, with $153.8 million in sales�last year. As the market continues to grow, I would look for more partnerships with large pharmaceutical companies, and of course more research and development dollars being devoted toward the chronic diabetic foot ulcers indication.
- [By John Udovich] Viropharma Inc. An international biopharmaceutical company, Viropharma has a pipeline focused on providing patients and physicians with new therapeutic alternatives for unmet medical needs where there are few treatment options available. In mid-September, Viropharma was soaring thanks to buyout rumors. Specifically, unnamed sources�have said that Viropharma was working with the Goldman Sachs Group Inc after attracting interest from suitors that include European drugmakers Sanofi SA (NYSE: SNY), which has been expanding into treatments of rare diseases since its 2010 acquisition of Genzyme Inc,�and Shire PLC (NASDAQ: SHPG), which develops treatments for rare illnesses such as Fabry disease. However, it should be noted that Deutsche Bank sees ViroPharma's base case valuation�at $38 per share, but the company's full value could be as high as $52 per share if the potential buyer has a Hereditary Angioedema sales force already in place. Bloomberg has since reported that the�JMP Group Inc. now says Viropharma could fetch as much as $60 a share while Akiva Felt of Oppenheimer has estimated the�company could fetch as much as $50 a share in a competitive bidding situation. On Monday, small cap Viropharma rose 0.26% to $39.26 (VPHM has a 52 week trading range of $22.12 to $40.89 a share) for a market cap of $2.57 billion plus the stock is up 76.5% since the start of the year, up 30% over the past year and up 186.1% over the past five years.
Top Shipping Stocks To Own For 2014: Petrotech Oil & Gas Inc (PTOG)
PetroTech Oil and Gas, Inc., formerly Unity Management Group, Inc., incorporated on April 10, 1998, operates and develops Enhanced Oil Recovery (EOR) opportunities within qualifying oil reservoirs in the United States using its Enhanced Oil Recovery method and technique. The company is also a construction and heavy equipment company. The Company is focussing on developing and acquisitions of technology in secondary oil recovery, oil and gas reporting software, trading software and Nitrogen and CO2 injection equipment. Enhanced oil recovery is also called improved oil recovery or tertiary recovery. The Company�� services include Work over and Installation Services, Heavy Equipment Services, Nitrogen, CO2 and Gas Mixture Treatments, Exhaust Gas Unit, Gas Assisted Gravity Drainage and Reservoir Development. During the year ended December 31, 2012, the Company acquired On Track Technology, Inc. On June 30, 2012, the Company acquired Metropolitan Computing Corp.
Work over and Installation Services
Drilling Vertical or Horizontal Well Supervision, Traditional Work over, Oilfield Work Over Rigs and Roustabout Services to be on location while recompletion, plugging or equipping of wells for in house leases and third party jobs as well. Where applicable Petrotech will utilize flexible Poly Urethane tubing for testing of wells and permanent installs for some shallow depths. The flexible tubing has a Paraffin�� and Asphalt Ines don�� stick to flexible tubing (as it does to steel tubing); and flexible tubing has an estimated 10 times longer life dependent upon the corrosiveness of production and by products, such as the water produced with hydrocarbons.
Heavy Equipment Services
Heavy Equipment Services includes heavy equipment, oilfield roustabout, crane work, water hauling, setting pumping units, separators, tanks, digging pitts and locations roads and heavy equipment services also includes highways for in house leases, third party oil companies and loca! l and government agencies.
Nitrogen, CO2 and Gas Mixture Treatments
The Company focuses in treating with Nitrogen, CO2 or a combination of the two; through two applications where applicable-Huff and Puff and Steady flooding. In cases, HoCyclic gas injection processes has been primarily restricted to the use of pure CO2 or CO2 that has been slightly contaminated.
Exhaust Gas Unit
The CO2/N2 gas mixture focuses to generated from a patented one-of-a-kind portable exhaust unit capable of producing 2.5 millions of cubic feet equivalent at 2000 psi. The exhaust unit manufacturing facility is capable of building over 100 million of daily of deliverability or 180,000 horse power of equipment per year.
Gas Assisted Gravity Drainage
Natural segregation of its gas mixture at miscibility pressure is a component in recreating a gas cap. Doubling of the primary oil recovery from a reservoir is expected with this EOR method and gas mixture. SPE paper #89357 documents GAGD recoveries averaging 63% of the OOIP.
Reservoir Development
Petrotech Oil and Gas Inc. focuses to use the technology in third dimension geophysics available, drilling and compositional reservoir modeling to devise the reservoir�� development plan. In some reservoirs has two horizontal wellbores; one each for the injection of gas and production of oil.
Advisors' Opinion:- [By Peter Graham]
Last Friday, small cap marijuana stock Petrotech Oil & Gas Inc (OTCMKTS: PTOG) surged 65.7% while OSL Holdings Inc (OTCMKTS: OSLH) and WebXU Inc (OTCMKTS: WBXU) sank 20.47% and 12.02%, respectively, thanks in part to news and (in the case of two of these small caps) some paid promotions or investor relations type of activities. But will these three small cap marijuana stocks be able to sustain their highs or come out of rehab this week? Here is a reality check before you look for a quick high with them:
Top Shipping Stocks To Own For 2014: Sonoco Products Company(SON)
Sonoco Products Company provides industrial and consumer packaging products, and packaging services worldwide. It offers composite paperboard cans; paperboard packages; fiber cartridges; layered bottles and jars; laminated tubs, cups, and spools; consumer and institutional trays; and aluminum, steel, and peelable membrane easy-open closures, as well as flexible packaging, product design, tool design, fabrication, and manufacturing services. The company also produces paperboard tubes, cores, roll packaging, molded plugs, pallets, pallet components, concrete forms, rotary die boards, recycled paperboard, chipboard, tube board, lightweight corestock, boxboard, linerboard, corrugating medium, specialty grades, and recovered paper products; and steel, nailed wooden, plywood, recycled, and polyfiber reels, as well as recycles old corrugated container, paper, plastic, metal, and glass materials. In addition, it manufactures custom-printed glass covers and coasters; offers custom packing, fulfillment, and primary package filling services, as well as operates scalable service centers; contract packaging, co-packing, and fulfillment services; and temporary, semipermanent, and permanent point-of-purchase displays. Further, the company provides fabricated foam, corrugated paperboard, molded EPS and EPP, antistatic fabricated foam solutions, nesting and stacking trays, molded foam dunnage, totes and tote inserts, energy-absorbing and flotation components, and insulation components, as well as contract package testing service. Additionally, it offers insulated shippers, durable transport chests, gel packs, phase change materials, lab/pharma/diagnostic specimen transport, refrigerant materials, edge and corner protection, and temperature assurance solutions; high-visibility packaging and printed products; and blister packaging machines. The company, formerly known as Southern Novelty Company, was founded in 1899 and is based in Hartsville, South Carolina. Advisors' Opinion:
- [By Rich Smith]
Hartsville, S.C.-based Sonoco Products (NYSE: SON ) is hiking prices on its signature product: cardboard.
On Friday, Sonoco announced an across-the-board price hike on "all grades of uncoated recycled paperboard (URB) products by $40 per ton, effective with shipments in the�United States and Canada�beginning July 8, 2013." The company's Primary Materials Group, North America, Vice President Marty Pignone�explained that "the�price increase�is necessary to recover rising recovered paper and other raw materials costs."
- [By David Fish]
Once known as the Southern Novelty Company, Sonoco Products (SON) is a leading producer of paper-based tubes and cores, flexible packaging, rigid plastic containers, cylinder paperboard, wire and cable reels, and point-of-purchase displays.
Top Shipping Stocks To Own For 2014: Worthington Industries Inc.(WOR)
Worthington Industries, Inc. operates as a diversified metals processing company focusing on steel processing and manufactured metal products in the United States, Canada, and Europe. It processes flat-rolled steel and stainless steel for the automotive, construction, lawn and garden, hardware, furniture, office equipment, electrical control, tubing, leisure and recreation, appliance, agricultural, HVAC, container, and aerospace markets. The company also produces low-pressure liquefied petroleum gas and refrigerant gas cylinders; high-pressure and industrial/specialty gas cylinders; seamless steel high pressure cylinders for compressed natural gas storage in motor vehicles; aluminum-lined, composite-wrapped high-pressure cylinders; airbrake tanks; and consumer products. In addition, it produces recovery tanks for refrigerant gases; air reservoirs for truck and trailer original equipment manufacturers; and Balloon Time helium kits. Further, the company designs and manufactu res reusable custom platforms, racks, and pallets made of steel for supporting, protecting, and handling products throughout the shipping process; provides framing systems and stairs for mid-rise buildings, and current and past model automotive service stampings; designs, builds, and supplies light gauge steel framed commercial structures and multi-family housing units; supplies and constructs metal framing products for single family housing with a focus on military housing; and manufactures pre-engineered steel egress stair solutions. Worthington Industries was founded in 1955 and is headquartered in Columbus, Ohio.
Advisors' Opinion:- [By Ben Levisohn]
Shares of Harsco have gained 4.7% to $26.43 today at 1:16 p.m., outpacing other construction & engineering companies. Dycom (DY) has advanced 0.5% to $30, KBR Inc. (KBR) has ticked up 0.1% to $33.03, Worthington Industries�(WOR) has risen 2.8% to $38.85�and Tutor Perini (TPC) has rallied 3.6% to $22.46.
- [By Yoshiaki Nohara]
Orix Corp., which provides leasing and loans, jumped 9.2 percent in Tokyo. Mizuno (8022) Corp. surged 18 percent after the Japanese sportswear company more than doubled its net-income forecast. Singapore Airlines Ltd. dropped 4.6 percent after posting a wider operating loss. WorleyParsons (WOR) Ltd., Australia�� largest oil and gas engineering company, plunged 13 percent after forecasting weaker earnings.
Top Shipping Stocks To Own For 2014: Ultra Petroleum Corp.(UPL)
Ultra Petroleum Corp., an independent oil and gas company, engages in the acquisition, exploration, development, production, and operation of oil and natural gas properties in the United States. It primarily focuses on developing a tight gas sand trend located in the Green River Basin of southwest Wyoming; and assessing, exploring, and developing its position in the Marcellus Shale and other horizons located in the north-central Pennsylvania area of the Appalachian Basin. As of December 31, 2011, the company owned interests in approximately 53,000 net acres in Wyoming covering approximately 190 square miles; 258,000 net acres in Pennsylvania; and 130,000 net acres in eastern Colorado?s Denver Julesburg Basin. Ultra Petroleum Corp. was founded in 1979 and is headquartered in Houston, Texas.
Advisors' Opinion:- [By Matt DiLallo]
The final company that's on my list is natural gas producer Ultra Petroleum (NYSE: UPL ) . Unlike Chesapeake and SandRidge, Ultra hasn't bet big on switching from natural gas to liquids. Instead, as a low-cost producer its focus has been on drilling profitable natural gas wells. The company made the decision to cut back on its growth plans and instead is investing within its cash flow. That strategy could make Ultra a big winner if gas prices improve further.
- [By Aimee Duffy]
Customer diversification and fee-based revenue are tough to beat. Let's look at some of QEP's top customers:
Anadarko Petroleum EOG Resources (NYSE: EOG ) Questar (NYSE: STR ) Ultra Resources, a subsidiary of Ultra Petroleum (NYSE: UPL )EOG Resources accounted for 11% of the midstream unit's revenue in 2012, while Questar accounted for 12%. Ultra is one of the two-largest shippers on QEP's Green River 60-mile crude oil pipeline (the other is Chevron).
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